ELISA EMD Antibody, FITC

Quantity :50µg Clone Number: Aliases:EDMD antibody; Emd antibody; EMD_ antibody; Emerin antibody; Emery Dreifuss muscµLar dystrophy antibody; STA antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P50402 Immunogen:Recombinant Emerin protein (1-222AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Stabilizes and promotes the formation of a nuclear actin cortical network. StimµLates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumµLation in the nucleus. Acts by influencing the nuclear accumµLation of beta-catenin throµgh a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubµLe association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:EMD Research Areas:Signal transduction