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ELISA PTPRB anti-

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Quantity :50µL Clone Number: Aliases:HPTP BETA antibody; HPTPB antibody; Phosphacan receptor type B antibody; Protein tyrosine phosphatase receptor type B antibody; Protein-tyrosine phosphatase beta antibody; PTPB antibody; Ptprb antibody; PTPRB_ antibody; R PTP BETA antibody; R-PTP-beta antibody; Receptor-type tyrosine-protein phosphatase beta antibody; RPTPB antibody; VascµLar endothelial protein tyrosine phosphatase antibody; VE-PTP antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P23467 Immunogen:Recombinant Receptor-type tyrosine-protein phosphatase beta protein (1758-1997AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. RegµLates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regµLator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel remodeling during embryonic development and determines blood vessel Quantity during perinatal growth. Essential for the maintenance of endothelial cell contact integrity and for the adhesive function of VE-cadherin in endothelial cells and this requires the presence of plakoglobin (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PTPRB Research Areas:Others

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