ELISA EIF4G2 anti-

Quantity :50µL Clone Number: Aliases:DAP-5 antibody; DAP5 antibody; Death associated protein 5 antibody; Death-associated protein 5 antibody; eIF-4-gamma 2 antibody; eIF-4G 2 antibody; eIF4G 2 antibody; EIF4G2 antibody; Eukaryotic translation initiation factor 4 gamma 2 antibody; IF4G2_ antibody; Nat1 antibody; Novel APOBEC-1 target 1 antibody; p97 antibody; Translation repressor NAT1 antibody; Translation repressor NAT1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P78344 Immunogen:Synthetic peptide of EIF4G2 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000 Background:Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-Aµg (Gµg) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:EIF4G2 Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology