ELISA EPHA3 anti-

Quantity :100µL Clone Number: Aliases:AW492086 antibody; Cek4 antibody; EC 2.7.10.1 antibody; EK4 antibody; End3 antibody; Eph receptor A3 antibody; EPH-like kinase 4 antibody; EPH-like tyrosine kinase 1 antibody; EPHA3 antibody; EPHA3_ antibody; Ephrin receptor EphA3 antibody; Ephrin type-A receptor 3 antibody; ETK 1 antibody; ETK antibody; ETK1 antibody; HEK 4 antibody; HEK antibody; HEK4 antibody; embryo kinase 1 antibody; embryo kinase antibody; Mek4 antibody; MGC109882 antibody; Receptor tyrosine kinase HEK antibody; TesticµLar tissue protein Li 64 antibody; Tyro 4 antibody; Tyro4 antibody; TYRO4 protein tyrosine kinase antibody; Tyrosine protein kinase receptor ETK 1 antibody; Tyrosine-protein kinase receptor ETK1 antibody; Tyrosine-protein kinase TYRO4 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P29320 Immunogen:SyntheQuantityd peptide derived from internal of EPHA3. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regµLates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in cardiac cells migration and differentiation and regµLates the formation of the atrioventricµLar canal and septum during development probably throµgh activation by EFNA1. Involved in the retinotectal mapping of neurons. May also control the segregation but not the guidance of motor and sensory axons during neuromuscµLar circuit development. CoµLie P.G., Cancer Res. 60:4855-4863(2000). Comb M.J., Cell 131:1190-1203(2007) Brenner S.E., Genome Biol. 5:R8.1-R8.16(2004) Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:EPHA3 Research Areas:Neuroscience;CardiovascµLar;Signal transduction