ELISA ELF4 anti-

Quantity :50µL Clone Number: Aliases:E74-like factor 4 antibody; ELF4 antibody; ELF4_ antibody; ELFR antibody; ETS-related transcription factor Elf-4 antibody; ETS-related transcription factor Elf4 antibody; MEF antibody; Myeloid Elf-1-like factor antibody; Myeloid Elf1-like factor antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q99607 Immunogen:Recombinant ETS-related transcription factor Elf-4 protein (1-200AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Transcriptional activator that binds to DNA sequences containing the consensus 5\\\'-WGGA-3\\\'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellµLar transformation throµgh inhibition of the p16 pathway. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ELF4 Research Areas:Epigenetics and Nuclear Signaling; Cancer