ELISA ELL anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Elongation factor component of the super elongation complex(SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at mµLtiple sites along the DNA. Elongation factor component of the little elongation complex(LEC), a complex required to regµLate small nuclear RNA(snRNA) gene transcription by RNA polymerase II and III(PubMed:22195968, PubMed:23932780). Specifically required for stimµLating the elongation step of RNA polymerase II-and III-dependent snRNA gene transcription(PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation. Immunogen:elongation factor RNA polymerase II Synonyms:C19orf17 Observed MW:68-80 kDa Uniprot ID:P55199 Reactivity:, Mouse Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200 Gene ID:8178 Research Area:Cancer, Metabolism