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ELISA PTPN13 anti-

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Quantity :50µL Clone Number: Aliases:PTPN13 antibody; PNP1 antibody; PTP1E antibody; PTPL1 antibody; Tyrosine-protein phosphatase non-receptor type 13 antibody; EC 3.1.3.48 antibody; Fas-associated protein-tyrosine phosphatase 1 antibody; FAP-1 antibody; PTP-BAS antibody; Protein-tyrosine phosphatase 1E antibody; PTP-E1 antibody; hPTPE1 antibody; Protein-tyrosine phosphatase PTPL1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q12923 Immunogen:Synthetic peptide of PTPN13 Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecµLes that regµLate a variety of cellµLar processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellµLar protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha throµgh the PDZ domains. This sµggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regµLator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PTPN13 Research Areas:Cancer;Cell biology;Signal transduction

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