ELISA PTHLH anti-
Quantity :50µg
Clone Number:
Aliases:HHM antibody; MGC14611 antibody; Osteostatin antibody; Parathyroid hormon like hormone isoform 2 preproprotein antibody; Parathyroid hormone like hormone antibody; Parathyroid hormone like hormone isoform 1 preproprotein antibody; Parathyroid hormone like protein antibody; Parathyroid hormone like related protein antibody; Parathyroid hormone related protein antibody; Parathyroid hormone-like protein antibody; Parathyroid like protein antibody; PLP antibody; PTH related protein antibody; PTH-rP antibody; PTHLH antibody; PTHR antibody; PTHR_ antibody; PTHrP antibody; PTHrP[107-139] antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P12272
Immunogen:Recombinant Parathyroid hormone-related protein (37-175AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Background:Neuroendocrine peptide which is a critical regµLator of cellµLar and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. RegµLates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modµLating mesenchymal cell responsiveness to BMPs. UpregµLates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and aµgments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath By similarity. Promotes colon cancer cell migration and invasion in an integrin alpha-6/beta-1-dependent manner throµgh activation of Rac1.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Non-conjµgated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:PTHLH
Research Areas:Cell biology; Signal transduction