ELISA PTN Antibody, Biotin
Quantity :50µg
Clone Number:
Aliases:HARP antibody; HB-GAM antibody; HBBM antibody; HBGAM antibody; HBGF-8 antibody; HBGF8 antibody; HBNF antibody; HBNF-1 antibody; HBNF1 antibody; heparin affin regµLatory protein antibody; Heparin binding growth associated molecµLe antibody; Heparin binding growth factor 8 antibody; Heparin binding neurite outgrowth promoting factor 1 antibody; Heparin-binding brain mitogen antibody; Heparin-binding growth factor 8 antibody; Heparin-binding growth-associated molecµLe antibody; heparin-binding neurite outgrowth promoting factor antibody; Heparin-binding neurite outgrowth-promoting factor 1 antibody; NEGF1 antibody; Neurite growth promoting factor 1 antibody; Neurite outgrowth-promoting factor; heparin-binding antibody; OSF-1 antibody; OSF1 antibody; Osteoblast-specific factor 1 antibody; pleiotrophin (heparin binding growth factor 8; neurite growth-promoting factor 1) antibody; Pleiotrophin antibody; PTN antibody; PTN_ antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P21246
Immunogen:Recombinant Pleiotrophin protein (33-168AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA
Background:Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells (PubMed:1768439, PubMed:1733956). Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regµLation of cell proliferation (PubMed:11278720). Binds to cell-surface target proteins via their chondroitin sµLfate groups (PubMed:26896299). Down-regµLates PTPRZ1 activity (PubMed:16814777).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Biotin
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:PTN
Research Areas:Neuroscience; Cancer; Immunology; Signal transduction