ELISA PTGS1 anti-

Quantity :100µL Clone Number: Aliases:COX 1 antibody; COX 3 antibody; COX-1 antibody; COX1 antibody; Cox3 antibody; Cyclooxygenase 1 antibody; Cyclooxygenase 3, included antibody; Cyclooxygenase-1 antibody; EC 1.14.99.1 antibody; Partial COX1 proteins, included antibody; PCOX1 antibody; PGG/HS antibody; PGH synthase 1 antibody; PGH1_ antibody; PGHS 1 antibody; PGHS-1 antibody; PGHS1 antibody; PHS 1 antibody; PHS1 antibody; Prostaglandin endoperoxide synthase 1 antibody; Prostaglandin G/H synthase 1 antibody; Prostaglandin H2 synthase 1 antibody; Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) antibody; Prostaglandin-endoperoxide synthase 1 antibody; PTGHS antibody; PTGS1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P23219 Immunogen:SyntheQuantityd peptide derived from COX1. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100 Background:Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particµLar in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascµLar smooth muscle cells. Lawrence M. Szewczuk, J. Biol. Chem., May 2004; 279: 22727 - 22737. Syed R. Baber, Am J Physiol Heart Circ Physiol, Oct 2005; 289: H1476 - H1487. Subhashini Chandrasekharan, J. Lipid Res., Dec 2005; 46: 2636 - 2648. K. Trent Moreland, J. Pharmacol. Exp. T Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PTGS1 Research Areas:Cancer?CardiovascµLar;Immunology?Metabolism;Signal transduction