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ELISA Phospho- (Tyr721) anti-

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Quantity :100µL Clone Number: Aliases:C Kit antibody; c-Kit antibody; c-Kit Ligand antibody; CD117 antibody; Kit antibody; Kit Ligand antibody; KIT oncogene antibody; KIT proto oncogene receptor tyrosine kinase antibody; KIT_ antibody; Mast cell growth factor receptor antibody; Mast/stem cell growth factor receptor Kit antibody; MGF antibody; p145 c-kit antibody; PBT antibody; Piebald trait protein antibody; Proto oncogene c Kit antibody; Proto oncogene tyrosine protein kinase Kit antibody; Proto-oncogene c-Kit antibody; SCF Receptor antibody; SCFR antibody; soluble KIT variant 1 antibody; Steel Factor Receptor antibody; Stem cell factor receptor antibody; tyrosine protein kinase Kit antibody; Tyrosine-protein kinase Kit antibody; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog antibody; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein antibody; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P10721 Immunogen:Peptide sequence around phosphorylation site of tyrosine 721 (N-E-Y(p)-M-D) derived from c-Kit. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:1000 Background:This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K) Nocka, K. et al. (1990) EMBO J. 9, 1805-1813. Hirota, S. et al. (1998) Science 279, 577-580. Blume-Jensen, P. et al. (2000) Nat. Genet. 24, 157-162. Sattler, M. et al. (1997) J. Biol. Chem. 272, 10248-10253. Gommerman, J.L. et al. (1997) J. Biol. Chem. 272, 30519-30525. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:KIT Research Areas:Neuroscience?Cancer;Developmental biology?Tags & Cell Markers?Immunology;Signal transduction?Stem cells

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