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ELISA PTPRJ anti-

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Quantity :50µL Clone Number: Aliases:CD 148 antibody; CD148 antibody; CD148 antigen antibody; Density enhanced phosphatase 1 antibody; Density-enhanced phosphatase 1 antibody; DEP 1 antibody; DEP-1 antibody; HPTP eta antibody; HPTPeta antibody; density enhanced phosphatase 1 antibody; Protein tyrosine phosphatase eta antibody; Protein tyrosine phosphatase receptor type J antibody; Protein tyrosine phosphatase receptor type J polypeptide antibody; Protein-tyrosine phosphatase eta antibody; Protein-tyrosine phosphatase receptor type J antibody; PTPJ antibody; Ptprj antibody; PTPRJ_ antibody; R PTP Eta antibody; R-PTP-eta antibody; R-PTP-J antibody; Receptor type tyrosine protein phosphatase eta antibody; Receptor-type tyrosine-protein phosphatase eta antibody; SCC 1 antibody; SCC1 antibody; susceptibility to colon cancer 1; mouse; homolog of antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q12913 Immunogen:Recombinant Receptor-type tyrosine-protein phosphatase eta protein (140-370AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, RET (variant MEN2A), KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Involved in vascµLar development. RegµLator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regµLator of platelet activation and thrombosis. Negative regµLator of cell proliferation. Negative regµLator of PDGF-stimµLated cell migration; throµgh dephosphorylation of PDGFR. Positive regµLator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation; throµgh KDR dephosphorylation. Negative regµLator of EGFR signaling pathway; throµgh EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regµLates T-cell receptor (TCR) signaling. Upon T-cell TCR activation, it is up-regµLated and excluded from the immunological synapses, while upon T-cell-antigen presenting cells (APC) disengagement, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regµLate prolongation of signaling. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PTPRJ Research Areas:Signal transduction

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