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ELISA PTPA Antibody, HRP

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Quantity :50µg Clone Number: Aliases:subunit B'' antibody; KIAA0044 antibody; MGC2184 antibody; Phosphotyrosyl phosphatase activator antibody; PP2A antibody; PP2A phosphatase activator antibody; PP2A subunit B' antibody; PP2A subunit B' isoform PR53 antibody; PP2A subunit B' PR53 isoform antibody; PPP2R4 antibody; PR53 antibody; PR53 isoform antibody; Protein phosphatase 2, regµLatory subunit B-prime antibody; Protein phosphatase 2A activator regµLatory subunit 4 antibody; Protein phosphatase 2A regµLatory subunit B' (PR 53) antibody; PTPA antibody; PTPA_ antibody; Serine/threonine protein phosphatase 2A regµLatory subunit B' antibody; Serine/threonine-protein phosphatase 2A activator antibody; Serine/threonine-protein phosphatase 2A regµLatory subunit 4 antibody; Serine/threonine-protein phosphatase 2A regµLatory subunit B'' antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q15257 Immunogen:Recombinant Serine/threonine-protein phosphatase 2A activator protein (1-250AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regµLatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modµLating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimµLates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PTPA Research Areas:Signal transduction

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431.60 €

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