ELISA PTK2 (Ab-397) anti-
Quantity :100µL
Clone Number:
Aliases:FADK 1 antibody; FADK antibody; FAK related non kinase polypeptide antibody; FAK1 antibody; FAK1_ antibody; Focal adhesion kinase 1 antibody; Focal adhesion Kinase antibody; Focal adhesion kinase isoform FAK Del33 antibody; Focal adhesion kinase related nonkinase antibody; FRNK antibody; p125FAK antibody; pp125FAK antibody; PPP1R71 antibody; Protein phosphatase 1 regµLatory subunit 71 antibody; Protein tyrosine kinase 2 antibody; Protein-tyrosine kinase 2 antibody; Ptk2 antibody; PTK2 protein tyrosine kinase 2 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q05397
Immunogen:Peptide sequence around aa. 395~399 (D-D-Y-A-E) derived from FAK.
Raised in:Rabbit
Reactivity:, Rat
Tested Applications:ELISA, WB; WB:1:500-1:1000
Background:
Important regµLator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regµLator of cyclin D-dependent kinases such as CDK4. RegµLated by phosphorylation and degradation events.
von Sengbusch A, et al. (2005) Am J Pathol ; 166(2): 585-596
Fornaro M, et al. (2000) Mol Biol Cell ; 11(7): 2235-2249
Zhang X, et al. (1999) Proc Natl Acad Sci U S A; 96(16): 9021-9026.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conjµgate:Non-conjµgated
Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:PTK2
Research Areas:Cancer?CardiovascµLar;Signal transduction