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ELISA PTK2 (Ab-397) anti-

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Quantity :100µL Clone Number: Aliases:FADK 1 antibody; FADK antibody; FAK related non kinase polypeptide antibody; FAK1 antibody; FAK1_ antibody; Focal adhesion kinase 1 antibody; Focal adhesion Kinase antibody; Focal adhesion kinase isoform FAK Del33 antibody; Focal adhesion kinase related nonkinase antibody; FRNK antibody; p125FAK antibody; pp125FAK antibody; PPP1R71 antibody; Protein phosphatase 1 regµLatory subunit 71 antibody; Protein tyrosine kinase 2 antibody; Protein-tyrosine kinase 2 antibody; Ptk2 antibody; PTK2 protein tyrosine kinase 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q05397 Immunogen:Peptide sequence around aa. 395~399 (D-D-Y-A-E) derived from FAK. Raised in:Rabbit Reactivity:, Rat Tested Applications:ELISA, WB; WB:1:500-1:1000 Background: Important regµLator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regµLator of cyclin D-dependent kinases such as CDK4. RegµLated by phosphorylation and degradation events. von Sengbusch A, et al. (2005) Am J Pathol ; 166(2): 585-596 Fornaro M, et al. (2000) Mol Biol Cell ; 11(7): 2235-2249 Zhang X, et al. (1999) Proc Natl Acad Sci U S A; 96(16): 9021-9026. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PTK2 Research Areas:Cancer?CardiovascµLar;Signal transduction

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