ELISA PTPN11 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecµLes that regµLate a variety of cellµLar processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regµLatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regµLation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
Immunogen:protein tyrosine phosphatase, non-receptor type 11
Synonyms:PTP2C, SHPTP2
Observed MW:71KDa
Uniprot ID:Q06124
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB, IHC
Recommended dilution:WB: 1:500 - 1:1000; IHC: 1:50 - 1:100
Gene ID:5781
Research Area:Signal Transduction, Metabolism, CardiovascµLar, Immunology, Developmental biology