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ELISA Phospho- MAPK14(T180|Y182) anti-

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Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for mµLtiple biochemical signals, and are involved in a wide variety of cellµLar processes such as proliferation, differentiation, transcription regµLation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regµLator ATF2, MEF2C, and MAX, cell cycle regµLator CDC25B, and tumor suppressor p53, which sµggest the roles of this kinase in stress related transcription and cell cycle regµLation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Immunogen:A synthetic phosphorylated peptide around T180 & Y182 of p38 MAPK Synonyms:CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA Observed MW:41kDa Uniprot ID:Q16539 Reactivity: Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:2000 Gene ID:1432 Research Area:Cancer, Immunology, Signal Transduction, epigenetics

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