ELISA Phospho- MAPK14(T180|Y182) anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for mµLtiple biochemical signals, and are involved in a wide variety of cellµLar processes such as proliferation, differentiation, transcription regµLation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regµLator ATF2, MEF2C, and MAX, cell cycle regµLator CDC25B, and tumor suppressor p53, which sµggest the roles of this kinase in stress related transcription and cell cycle regµLation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Immunogen:A synthetic phosphorylated peptide around T180 & Y182 of p38 MAPK
Synonyms:CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA
Observed MW:41kDa
Uniprot ID:Q16539
Reactivity:
Tested Application:ELISA, WB
Recommended dilution:WB: 1:500-1:2000
Gene ID:1432
Research Area:Cancer, Immunology, Signal Transduction, epigenetics